Monkeypox – WHO declares a global emergency

23.07.2022
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Monkeypox – WHO declares a global emergency

Monkeypox has been all over the news worldwide the last few months.

It is caused by the monkeypox virus, which belongs to a subset of the Poxviridae family of viruses called Orthopoxvirus.

This subset includes:

  1. Smallpox
  2. Vaccinia
  3. Cowpox viruses

The virus is endemic in some animal populations in a number of countries, leading to occasional outbreaks among local people and travelers.

Global Emergency

The expanding monkeypox outbreak in more than 70 countries is now considered a global emergency, according to the head of the World Health Organization. This declaration, made on Saturday, may encourage additional funding for the once-rare disease’s treatment and exacerbate the competition for limited vaccine supplies.

Despite the emergency committee’s members being divided, WHO Director-General Tedros Adhanom Ghebreyesus decided to make the declaration. It was the first time the head of the UN health organization had done something like that.

“We have an outbreak that has spread around the world rapidly through new modes of transmission about which we understand too little and which meets the criteria in the international health regulations,” Tedros said.

“I know this has not been an easy or straightforward process and that there are divergent views among the members” of the committee, he added.

Monkeypox has existed in some areas of central and west Africa for decades, but until May, when officials discovered dozens of infections in Europe, North America, and other places, it was not known to cause significant outbreaks outside of the continent or to spread significantly among people.

When a worldwide emergency is declared, it signifies that the monkeypox outbreak is an “exceptional event”, and that it may spread to other nations and necessitates a coordinated international response. For public health emergencies like the COVID-19 pandemic, the 2014 West African Ebola outbreak, the Zika virus in Latin America in 2016, and the ongoing campaign to eradicate polio, WHO has already proclaimed emergencies.

The emergency declaration mainly acts as an appeal to focus more resources and attention on an outbreak on a worldwide scale. Previous announcements

WHO’s top monkeypox expert, Dr. Rosamund Lewis, said this week that 99% of all the monkeypox cases beyond Africa were in men and that of those, 98% involved men who have sex with men. Experts suspect the monkeypox outbreaks in Europe and North America were spread via sex at two raves in Belgium and Spain.

“Although I am declaring a public health emergency of international concern for the moment, this is an outbreak that is concentrated among men who have sex with men, especially those with multiple sexual partners,” Tedros said.

“That means that this is an outbreak that can be stopped with the right strategies in the right groups.”

Monkeypox spreads differently from COVID-19

WHO advises individuals to stay informed on the severity of the outbreak in their community (if there is one), the symptoms, and prevention from trustworthy sources, such as national health authorities.

The fact that it spreads through close touch, as opposed to how COVID-19 spreads, is an essential factor.

Health professionals, family members, and romantic partners who have frequent close contact with infectious people are more likely to become ill.

It is never appropriate to stigmatize a group of people because they have an illness. It can be a challenge to contain an outbreak since it discourages people from seeking medical attention and promotes undetected spread.

  • For more updates, you can visit the official WHO website.

Monkeypox is usually associated with travel to Central or West Africa. Interestingly enough, cases that have been occurring outside these countries haven’t traveled there.

As it has already been stated, it can be spread via close contact with an infected person. The virus can enter the body through:

  • Broken skin
  • Through the eyes, nose or mouth
  • Direct sexual contact
  • Touching clothing, bedding or towels used by someone with the monkeypox rash
  • Touching monkeypox skin blisters or scabs
  • The coughs or sneezes of a person with the monkeypox rash

Symptoms

In humans, the symptoms of monkeypox are similar to but milder than the symptoms of smallpox. Monkeypox begins with fever, headache, muscle aches, and exhaustion.  The incubation period (time from infection to symptoms) for monkeypox is usually 7−14 days but can range from 5−21 days.

The illness begins with:

  • Fever
  • Headache
  • Muscle aches
  • Backache
  • Swollen lymph nodes
  • Chills
  • Exhaustion

Within 1 to 3 days (sometimes longer) after the appearance of fever, the patient develops a rash, often beginning on the face then spreading to other parts of the body.

Lesions progress through the following stages before falling off:

  • Macules
  • Papules
  • Vesicles
  • Pustules
  • Scabs

The illness typically lasts for 2−4 weeks.

Two different strains

We are aware of two different strains of monkeypox. The so-called West African strain, with a case-fatality rate between 1 and 3 percent, is the one that affects Nigeria, Liberia, Sierra Leone, and Côte d’Ivoire. This one was found in the most recent instances in Europe. The second is the “Congo Basin” strain, which is present in Gabon, the Central African Republic (CAR), the Democratic Republic of the Congo (DRC), and the Republic of the Congo. Both strains are currently in circulation in Cameroon. Most recently, infections thought to be caused by the West African strain, which was imported from Nigeria, have been documented. The Congo Basin strain has a case-fatality rate of about 10% and is linked to more severe clinical manifestations.

The fact that these statistics come from nations with rather underdeveloped medical systems, particularly in more rural areas, must also be kept in mind.

Because of the “Congo Basin” strain, in Africa, monkeypox has been shown to cause death in as many as 1 in 10 persons who contract the disease, that i because the strain of monkeypox virus that has infected people there is more virulent, with a mortality rate of about 10%.

Mortality

Most cases are mild and people tend to recover within weeks. But the death rate varies, depending on the type. The ECDC has said that the west African clade, the type so far seen in Europe, has a case fatality rate of around 3.6% (estimated from studies conducted in African countries). Mortality is higher in children, young adults, and immunocompromised.

There have been a total of 17,058 confirmed cases as of July 23. 72 recorded deaths have occurred since the year 2022 began, all of them in Africa.

Treatment

According to the CDC, there’s no proven treatment for monkeypox specifically, but the smallpox vaccine, antivirals, and vaccinia immune globulin can be used.

The federal government though, has a stockpile of other smallpox virus vaccines that can be used. The smallpox vaccination programme has stopped in the U.S. back in 1972. There is a possibility that people who have received the vaccine back then, might have some immunity.

There are no proven antivirals specific to monkeypox. Some treatments though may be used.

Sources

medpagetoday.com

beta.ctvnews.ca

cdc.gov

who.int

scientificamerican.com

https:

nature.com

en.m.wikipedia.org

gavi.org

theguardian.com

 

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